familial focal epilepsy with variable foci true FFEVF Orphanet:98820 MONDO:0020310 UMLS:CN207131 GARD:0013295 This is a hereditary epilepsy, with focal seizures arising in different focal regions in different family members but with each individual in a family having a single focal seizure type. There are no implications expected for development or learning and seizures are typically infrequent and well controlled. familial partial epilepsy with variable foci Familial focal epilepsy with variable foci is a rare genetic epilepsy disorder characterized by autosomal dominant lesional and nonlesional focal epilepsy with variable penetrance. Focal seizures emanate from different cortical locations (temporal, frontal, centroparietal, parietal, parietaloccipital, occipital) in different family members, but for each individual a single focus remains constant throughout lifetime. Seizure type (tonic, tonic-clonic or hyperkinetic) and severity varies among family members and tends to decrease (but do not disappear) during adulthood. Many patients have an aura and show automatisms during diurnal seizures whereas others have nocturnal seizures. Most individuals are of normal intelligence but patients with intellectual disability, autistic spectrum disorder and obsessive-compulsive disorder have been described. SCTID:764522009 variable age onset epilepsy