secondary neoplasm metastatic neoplasm metastatic disease A tumor that has spread from its original (primary) site of growth to another site, close to or distant from the primary site. Metastasis is characteristic of advanced malignancies, but in rare instances can be seen in neoplasms lacking malignant morphology. NCIT:C3261 Metastatic Tumor metastatic tumor Note that we currently treat secondary neoplasms as being neoplastic diseases that are derived from neoplasm; classes such as 'neoplasm', 'carcinoma' are implicitly primary. This may change in future. MONDO:0024883 ICDO:8000/6 metastatic neoplasm http://www.case.edu/EpSO.owl#MetastaticTumor