childhood-onset epilepsy syndrome atypical childhood epilepsy with centrotemporal spikes 2018-06-22T22:43:29Z true MONDO:0100020 atonic-benign childhood epilepsy with centrotemporal spikes pseudo-Lennox syndrome A childhood-onset epilepsy that is characterized by frequent seizures of multiple types, including nocturnal focal motor and fronto-parietal opercular seizures, and daytime focal motor seizures with negative myoclonus and atypical absence seizures. Centrotemporal sharp waves are seen on EEG. During the phase of the epilepsy when seizures are frequent, neuropsychological deficits and motor impairment may be present. These deficits improve when seizures remit. atypical benign partial epilepsy of childhood Atypical childhood epilepsy with centrotemporal spikes (previously known as pseudo-Lennox syndrome, atypical benign partial epilepsy of childhood and atonic-benign childhood epilepsy with centrotemporal spikes) is recognized as an atypical evolution of childhood epilepsy with centrotemporal spikes. This syndrome is self-limiting, but characterized by frequent seizures of multiple types, including nocturnal focal motor and fronto-parietal opercular seizures, and daytime focal motor seizures with negative myoclonus and atypical absence seizures. Centrotemporal sharp waves are seen on EEG. During the phase of the epilepsy when seizures are frequent, neuropsychological deficits and motor impairment may be present. These deficits improve when seizures remit.