Cyclical Vomiting true NICHD A periodic syndrome that is commonly a migraine precursor and is characterized by recurrent, self-limiting episodes of vomiting associated with intense nausea, pallor, and lethargy. Cyclical vomiting is characterized by stereotyped periods of recurrent vomiting which may last hours to days and may be separated by weeks during which the individual has no symptoms. It is considered a migraine variant as there is often a family history of migraine headache, though the pathophysiology is not well understood. Usually no trigger to a particular episode can be defined. Recurrent vomiting may produce physiological disturbance but awareness should not be impaired and the attacks are longer than expected in focal seizures. Episodes may begin in early childhood and evolve into abdominal migraine and then to classic migraine with headache. If the vomiting persists into adult life it remains paroxysmal but may be less cyclical in nature. C0152164 Cyclical Vomiting Cyclic vomiting syndrome MedDRA A condition characterized by recurrent, self-limiting episodes of vomiting associated with intense nausea, pallor, and lethargy. It is commonly a migraine precursor. Cyclical Vomiting Cyclical Vomiting Finding C117014 migraine associated disorder