signal transduction phosphatidylinositol 3-kinase signaling pathway true https://www.ncbi.nlm.nih.gov/pubmed/17910583 KEGG:04070 PW:0000595 Phosphatidylinositol kinases represent a family of lipid kinases that phosphorylate the 3' position of the inositol ring in target substrates. They are grouped into three classes: class I further subdivided into subclass A and B, class II and class III. By far the best known and characterized is class I, particularly IA that signals downstream of receptor tyrosine kinases and engages the Akt family of kinases. PI3K-pathway PI3K signaling pathway phosphatidylinositol 3-kinase pathway - give exact synonym phosphoinositide 3-kinase signaling pathway pathway