Vertebrata <vertebrates> hypothalamus true MA:0000173 BAMS:HY preoptico-hypothalamic region galen:Hypothalamus Part of the diencephalon ventral to the thalamus consisting of connecting fibers and is a center for control of the autonomous nervous system.[AAO] MBA:1097 TAO:0000032 BIRNLEX:734 hypothalamus all vertebrates contain a hypothalamus HBA:4540 AAO:0010484 FMA:62008 UBERON:0001898 BAMS:Hy MAT:0000112 ZFA:0000032 EV:0100225 OpenCyc:Mx4rwEgr9JwpEbGdrcN5Y29ycA BTO:0000614 For instance, the vertebrate ventral diencephalon generates the hypothalamus which functions as a major endocrine center in cooperation with the hypophysis, the anterior part of the pituitary gland, located just ventral to the hypothalamus. In the amphioxus brain, the presence of a hypothalamus-like structure has been reported associated with the ventrally located Hatschek's pit, the hypothetical hypophysial homologue. It is thus conceivable that a hypothalamus-like structure originally involved in endocrine functions may have already been present before the establishment of vertebrates.[well established][VHOG] hypothalamic CALOHA:TS-0469 http://braininfo.rprc.washington.edu/centraldirectory.aspx?ID=292 GAID:460 preoptico-hypothalamic area http://www.case.edu/EpSO.owl#HypothalamusZone Hy EMAPA:17536 EHDAA2:0000802 EFO:0000107 A specialized brain region of the ventral diencephalon arising near the end of the segmentation period; the embryonic hypothalamic region will give rise to the posterior pituitary gland as well as a number of brain nuclei. Kimmel et al, 1995.[TAO] NCIT:C12458 DHBA:10467 VHOG:0000179 MESH:A08.186.211.577.482 BM:Die-Hy MIAA:0000112 XAO:0004070 uberon A specialized brain region of the ventral diencephalon arising near the end of the segmentation period; the embryonic hypothalamic region will give rise to the posterior pituitary gland as well as a number of brain nuclei. [ZFA]. One of the most important functions of the hypothalamus is to link the nervous system to the endocrine system via the pituitary gland (hypophysis).[Wikipedia]. EHDAA:5446 UMLS:C0020663 regional part of brain