signal transduction
G protein-coupled receptor signaling pathway
true
G-protein coupled receptor protein signal transduction
GO:0038042
GPCR signaling pathway
dimeric G-protein coupled receptor signalling pathway
https://www.ncbi.nlm.nih.gov/pubmed/26721354
MIPS_funcat:30.05.02.24
G-protein-coupled receptor protein signalling pathway
G-protein coupled receptor signaling pathway via GPCR dimer
A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane.
MIPS_funcat:30.01.05.05
biological_process
G-protein coupled receptor signalling pathway
dimeric G-protein coupled receptor signaling pathway
G protein coupled receptor protein signaling pathway
GPCR signalling pathway
G protein coupled receptor protein signalling pathway
G-protein coupled receptor protein signaling pathway
GO:0007186