astrocytoma left frontal astrocytoma http://www.case.edu/EpSO.owl#LeftFrontalAstrocytoma Modified definition https://rarediseases.org/rare-diseases/anaplastic-astrocytoma/ Anaplastic astrocytomas developed in the left frontal lobe of the cerebrum. A tumor in the frontal lobe may cause memory problems, changes in personality and mood, and paralysis (hemiplegia) on the side of the body opposite of the tumor.