neonatal/infantile epilepsy syndrome self-limited familial and non-familial infantile epilepsy true Familial (and non-familial) infantile epilepsy, formerly called benign familial (and non-familial) infantile seizures, is a syndrome characterized by the onset of seizures in the infantile period. Seizures are often frequent and intractable at onset but spontaneously resolve. The child is expected to have normal developmental progress. Familial and non-familial forms of infantile epilepsy are identical except for the presence of a family history. Familial cases show autosomal dominant inheritance and have genetic etiologies in common with self-limited familial neonatal and self-limited familial neonatal-infantile epilepsies, thus these epilepsy syndromes are likely related disorders.