life cycle stage adult stage 15.0 HPO (Human Phenotype Ontology) considers HP:0003581 (adult onset) as 'at the age of 16 years or later', but this adult stage directly follows the pediatric onset (HP:0410280) defined 'as before the age of 15 years' (see https://github.com/obophenotype/human-phenotype-ontology/issues/6099). To be consistent, we consider adult stage as starting at 15 years. HsapDv:0000258 mature stage HP:0003581 human_developmental_stage UBERON:0000113 Human developmental stage that refers to a sexually mature human.