dpp Hin-d DmDPP M(2)LS1 decapentaplegic TGF-beta M(2)23AB DPP-C heldout Tgfbeta Dm-DPP Haplo-insufficient shv DPP Dpp blink TGF-b ho l(2)10638 bone morphogenetic protein Tegula Tg bone morphogenic protein Dpp/TGFbeta l(2)k17036 shortvein Decapentaplegic/Bone Morphogenetic Protein blk BMP Bmp l(2)22Fa CG9885 TGFbeta Decapentaplegic gene