has characteristic electrically_synapsed_to has soma location fasciculates with overlaps capable of part of has synaptic IO in region receives synaptic input in region receives synaptic input from neuron supraesophageal ganglion neuron giant fiber neuron GFN GF interneuron VFB:FBbt_00004020 DNlt002 FBbt:00004020 Large adult descending neuron that controls jump escape behavior (Thomas and Wyman, 1984).There is one of these cells per hemisphere (Koto et al., 1981; Namiki et al., 2018; Sturner et al., 2025) and its large cell body is located posterior to the lower protocerebrum (Koto et al., 1981). It can be identified by its large descending axon (Power, 1948), which is several times larger than any other axon in the cervical connective (Koto et al., 1981). It enters the cervical connective via the posterior cerebro-cervical fascicle (Ito et al., 2014) and descends on the ipsilateral side (Koto et al., 1981; Namiki et al., 2018), in the dorsal cervical fasciculus (Power, 1948). In the brain, it has dendritic arborization in the ipsilateral zones A and B of the antennal mechanosensory and motor center (Kamikouchi et al., 2009; Matsuo et al., 2016), where it receives substantial input from zone A and B Johnston organ neurons (Kim et al., 2020). It also arborizes in the posterior ventrolateral protocerebrum and gorget (Matsuo et al., 2016; Namiki et al., 2018). It enters the VNC near the dorsal midline and extends posteroventrally to the mesothoracic neuromere, where it turns ventrolaterally, and ends abruptly without branching (Koto et al., 1981). In the mesothoracic neuromere, it forms electrical synapses with downstream motor and premotor neurons at the inframedial bridge, where the two giant fiber neurons connect across the midline, and at the axonal lateral bend (King and Wyman, 1980; Allen et al., 1998; Kennedy and Broadie, 2018). It is a primary neuron (Allen et al., 1998; Dorkenwald et al., 2024; Schlegel et al., 2024). AMMC projection neuron, Giant Fiber GF CGF giant fibers descending neuron of the posterior brain DNp01 Some components identified by Power (1948) later found to be electrically-coupled neurons (King and Wyman, 1980; Phelan et al., 1996). fly_anatomy.ontology DNp01 giant fiber interneuron aPN(GF) DNp01 GFI cervical giant fiber neuron adult subesophageal sensory interneuron mesothoracic tergotrochanter muscle motor neuron peripherally synapsing interneuron gorget posterior ventrolateral protocerebrum descending neuron of the posterior brain adult dorsal cervical fasciculus giant fiber coupled neuron 1 giant fiber coupled neuron 2 giant fiber coupled neuron 3 giant fiber coupled neuron 4 adult inframedial bridge cell body rind of adult protocerebrum primary interneuron zone A Johnston organ neuron zone B Johnston organ neuron antennal mechanosensory and motor center zone A antennal mechanosensory and motor center zone B posterior cerebro-cervical fascicle auditory system neuron antennal mechanosensory and motor center A1 projection neuron adult posterior brain cell body rind jump response bilateral