has characteristic has soma location fasciculates with capable of part of expresses receives synaptic input in region sends synaptic output to region receives synaptic input from neuron Nplp1 DN1 neuron adult lateral horn posterior optic commissure DN1a neuron fly_anatomy.ontology Adult DN1 neuron with its soma in the anterior superior brain, dorsal to the superior lateral protocerebrum (SLP) (Shafer et al., 2006; Reinhard et al., 2022). It is glutamatergic and also expresses Nplp1 (IPNamide) and CCHamide1 (Shafer et al., 2006; Collins et al., 2012; Fujiwara et al., 2018; Reinhard et al., 2022) and Dh44 (Reinhard et al., 2024). It arborizes ipsilaterally in the ventromedial posterior lateral horn and the lateral and dorsal mushroom body accessory calyces with mixed pre- and post-synaptic terminals (Bates et al., 2020; Marin et al., 2020; Reinhard et al., 2022). A ventral projection extends to the posterior optic commissure and follows it laterally, reaching the accessory medulla, where it has mainly presynaptic terminals (Bates et al., 2020; Marin et al., 2020; Reinhard et al., 2022). A large amount of input is from the thermosensory VP3 vPN and VP2 adPN neurons (Marin et al., 2020; Alpert et al., 2020). Activity of the cold-responsive VP3 vPN has a strong inhibitory effect on DN1a (Alpert et al., 2020). There are two of these cells per hemisphere and they are primary neurons (Shafer et al., 2006; Bates et al., 2020). One of these cells per hemisphere additionally extends a branch dorsally into the SLP (Reinhard et al., 2022). FBbt:00007429 DN1a VFB:FBbt_00007429 DN1a anterior DN1 neuron accessory medulla adult mushroom body dorsal accessory calyx primary neuron adult antennal lobe projection neuron VP2 adPN adult lateral horn neuron CCHamide-1 neuron adult mushroom body lateral accessory calyx adult Dh44 neuron of brain cell body rind of adult dorsal superior lateral protocerebrum accessory medulla neuron adult glutamatergic neuron adult antennal lobe projection neuron VP3 vPN response to temperature stimulus unilateral