receives synaptic input in region sends synaptic output to region medulla layer M1 adult gnathal ganglion superior posterior slope inferior posterior slope adult subesophageal zone output neuron primary interneuron adult octopaminergic AL2b2 neuron 2025-04-15T14:36:58Z fly_anatomy.ontology FBbt:00053405 OA-AL2b2 aMe14b Octopaminergic neuron of the AL2 cluster which innervates the ipsilateral and contralateral outer medulla (Busch et al., 2009; Eckstein et al., 2024; Nern et al., 2025). In the medulla, it is mainly presynaptic, sending output to around 150-200 columns of layer M1, with more synapses and more column coverage in the ipsilateral medulla (Nern et al., 2025). It has its soma ventral-medial to the antennal lobe and is a putative embryonic-born neuron (Schlegel et al., 2024; Dorkenwald et al., 2024). Its main process extends posteriodorsally from the soma, close to the esophageal foramen, then bifurcates in the posterior brain, projecting to both optic lobes (Busch et al., 2009; Dorkenwald et al., 2024; Schlegel et al., 2024; Nern et al., 2025). In the central brain, it receives input in the ipsilateral inferior and superior posterior slope, and the gnathal ganglion (Schlegel et al., 2024; Dorkenwald et al., 2024). There are two of these cells per hemisphere (Nern et al., 2025). MeVCMe1 VFB:FBbt_00053405 OA-AL2b2 Neurotransmitter not confirmed by immunostaining by Busch et al. (2009). Identified in EM data in Nern et al. (2025) and Schlegel et al. (2024) and predicted to be octopaminergic. adult visual centrifugal neuron octopaminergic AL2b neuron