has characteristic overlaps capable of part of expresses has synaptic IO in region receives synaptic input in region sends synaptic output to region InR protocerebral bridge male organism adult lateral horn ventrolateral protocerebrum anterior superior medial protocerebrum adult doublesex pC1 (male) neuron adult central complex neuron adult fruitless pMP-e neuron adult fruitless P1 (male) neuron 2013-07-25T20:49:01Z https://github.com/FlyBase/drosophila-anatomy-developmental-ontology/issues/106 fru-P neuron FBbt:00110621 adult fruitless pMP-e (male) neuron Male-specific fruitless neuron with its soma in the dorsal posterior brain, mediolateral to the mushroom body (Kimura et al., 2008). It develops from the DM4 neuroblast (Ren et al., 2016). It extends a primary neurite anterodorsally, which ramifies extensively toward the lateral and medial protocerebrum regions (Kimura et al., 2008). A long prominent neurite crosses the midline through the anterior superior medial protocerebrum, ending at the corresponding contralateral region (Kimura et al., 2008). It has presynaptic sites in the protocerebral bridge (Duhart et al., 2020). These neurons are a subset of the doublesex pC1 neurons (Zhou et al., 2015). It is involved in the decision to initiate courtship song, including pulse and sine song (Philipsborn et al., 2011; O'Sullivan et al., 2018). Its activity can also suppress sleep (Duhart et al., 2020). It expresses the insulin receptor (InR) and is suppressed by insulin from the insulin producing cells of the pars intercerebralis (Zhang et al., 2022). There are approximately 50 of these cells per hemisphere (Ren et al., 2016). adult male fruitless pMP4 neuron fly_anatomy.ontology adult male fruitless pMP-e neuron fru-P1 VFB:FBbt_00110621 pC1 has been listed as an exact synonym for this in the past, but pC1 is actually a type of doublesex-expressing neuron (Rideout et al., 2010 - FBrf0210397), which now has its own class - FBbt:00047348. pMP-e (P1) is a subset of pC1 (Zhou et al., 2015). fru-P1 sleep male courtship behavior, veined wing generated song production bilateral