makes_use_of cryofixed tissue transmission electron microscopy cryogenic transmission electron microscopy 2026-02-16T12:43:02Z cryogenic-sample electron microscopy cryo-transmission electron microscopy A form of transmission electron microscopy in which the specimen is maintained in a vitrified state at cryogenic temperature throughout imaging. The specimen is rapidly frozen to preserve its native structure in amorphous ice, avoiding the artefacts associated with chemical fixation, dehydration, and staining. Imaging is performed with the specimen held at cryogenic temperature in a transmission electron microscope. cryoEM cryogenic electron microscopy cryo-EM cryo-TEM cryo-electron microscopy