has soma location receives synaptic input in region sends synaptic output to region receives synaptic input from neuron adult optic lobe neuron medulla layer M1 medulla layer M2 medulla layer M3 medulla layer M4 medulla layer M8 lobula layer 6 visual system neuron cell body rind of adult anterior medulla medulla-lobula neuron 1 2022-03-14T13:52:14Z medulla-to-lobula cell ML1 amacrine-like cell VFB:FBbt_00052137 MLt1 adult CB3833 neuron adult medulla-lobula neuron MeLo1 ML1 CB3833 fly_anatomy.ontology Optic lobe neuron that has its soma in the anterior medulla cell body rind, multicolumnar dendritic innervation of the medulla, and an axon that reaches the anterior lobula without passing through the second optic chiasm (Kind et al., 2021). Its dendritic arborization spans approximately 20 optic columns, ramifying in layers M1-4 and M8 from vertical processes (Kind et al., 2021). It receives synaptic input from R8 photoreceptors, mainly in pale optic columns (Kind et al., 2021). Its axon leaves the distal medulla and travels anteriorly to reach layer 6 of the lobula, where it has postsynapses in a few columns (Kind et al., 2021; Nern et al., 2025). In a subpopulation of these cells its axon also innervates the central brain (Kind et al., 2021). It is predicted to be cholinergic (Eckstein et al., 2024; Nern et al., 2025). There are around 45 of these cells per optic lobe (Kind et al., 2021; Nern et al., 2025). FBbt:00052137 MeLo1 ML1 adult ML1 neuron adult cholinergic neuron optic lobe wide-field columnar neuron photoreceptor cell R8 of pale ommatidium