has characteristic has soma location develops from capable of part of receives synaptic input in region sends synaptic output to region receives synaptic input from neuron sends synaptic output to cell supraesophageal ganglion neuron superior medial protocerebrum adult crepine mushroom body anterior layer of beta' lobe slice 2 larval mushroom body output neuron k1 adult typical mushroom body output neuron adult SMPad3 lineage neuron primary interneuron adult glutamatergic neuron adult dopaminergic PAM neuron mushroom body output neuron 1 2010-09-09T02:45:15Z FlyBrain_NDB:10459 fly_anatomy.ontology Synapsing with PAM neurons determined by GRASP (Owald et al., 2015). VFB:FBbt_00100234 MBON01 MBON01 A bilateral, glutamatergic neuron whose cell body is located on the superior neuropils, anterior to the pars intercerebralis of the adult brain (Tanaka et al., 2008; Aso et al., 2014). The cell body fiber travels ventrally towards the medial lobe, arborizing in the anterior layer of beta' lobe slice 2 and the most medial segment of the gamma lobe (slice 5) (Tanaka et al., 2008). The main fiber then enters the opposite gamma lobe, arborizes in the beta' lobe slice 2 and gamma lobe slice 5. The major axon projects ipsilaterally to the superior medial protocerebrum (SMP), whereas a very thin axon projects to the crepine and SMP in the other hemisphere. There is one neuron of this type per hemisphere (Aso et al., 2014; Li et al., 2020). It develops from the larval MBON-k1 (Truman et al., 2023). These neurons have synaptic connections with protocerebral anterior medial (PAM) cluster neurons in the SMP and in the tip of the mushroom body horizontal lobe (Owald et al., 2015). It is involved in the retrieval of long term memory associated with water reward (Shyu et al., 2017) as well as medium and long term aversive memory (Bouzaiane et al., 2015). MB-M6 MBON-01 MBON-gamma5beta'2a M6 mushroom body medial lobe arborizing neuron 6 FBbt:00100234 mushroom body gamma lobe slice 5 adult superior brain cell body rind long-term memory medium-term memory bilateral