has soma location fasciculates with receives synaptic input in region sends synaptic output to region supraesophageal ganglion neuron adult gnathal ganglion anterior ventrolateral protocerebrum inferior clamp saddle flange primary neuron adult leg neuropil lower tectulum descending neuron of the posterior brain ventral median tract of ventral cervical fasciculus adult cholinergic neuron cell body rind of adult posterior lateral protocerebrum descending neuron of the posterior brain DNp45 2024-07-25T12:00:00Z DNp45 DNxn078 fly_anatomy.ontology Adult descending neuron with its soma in the brain, posterior to the posterior lateral protocerebrum (Schlegel et al., 2024; Dorkenwald et al., 2024). It is a putative embryonic-born neuron (Schlegel et al., 2024; Dorkenwald et al., 2024). In the brain, it has postsynapses in the ipsilateral anterior ventrolateral protocerebrum and inferior clamp, and presynapses in the gnathal ganglion, the saddle and the ipsilateral flange (Schlegel et al., 2024; Dorkenwald et al., 2024). Within the VNC, it fasciculates with the ventral median tract of ventral cervical fasciculus and sends output to the leg neuropil and lower tectulum (Takemura et al., 2024; Marin et al., 2024). Its predicted neurotransmitter is acetylcholine (Eckstein et al., 2024). There are approximately 2 of these cells per organism (Schlegel et al., 2024; Dorkenwald et al., 2024; Sturner et al., 2025). FBbt:20011346 DNp45 VFB:FBbt_20011346 Type identified at light level and matched across EM datasets by Sturner et al. (2025). Pre- or post-synapse locations are those with the highest total count of these neurons in FlyWire FAFB.