part_of part of part of capable of capable of material entity keratinizing barrier epithelial cell keratinocyte cell FMA:62879 CALOHA:TS-0500 malpighian cell keratinized cell of epidermis Keratinocytes are reportedly CDw210a-negative, CDw210b-positive, CD281-positive, CD282-positive, CD285-positive, IL22Ra1-positive, Human keratinocytes are reportedly capable of secreting BD-2, BD-3, hCAP-18, CXCL1, CXCL5, CXCL8, elafin, MMP-3, NGAL, PDGF-A, S100A7, S100A8, and S100A9. Transcription factors: STAT3-positive. CL:0002185 BTO:0000667 An epidermal cell which synthesizes keratin and undergoes a characteristic change as it moves upward from the basal layers of the epidermis to the cornified (horny) layer of the skin. Successive stages of differentiation of the keratinocytes forming the epidermal layers are basal cell, spinous or prickle cell, and the granular cell. epidermal cell antimicrobial peptide production antimicrobial peptide secretion positive regulation of neutrophil chemotaxis skin epidermis