regulates regulates process has causal agent lipid chemical synaptic transmission trans-synaptic signaling trans-synaptic signaling by lipid trans-synaptic signaling, modulating synaptic transmission trans-synaptic signaling by lipid, modulating synaptic transmission Cell-cell signaling between presynapse and postsynapse, via the release and reception of lipid molecules, that modulates the synaptic transmission properties of the synapse. biological_process Note that this term was created for the SynGO project, and will be obsoleted when the SynGO annotations are made in Noctua. GO:0099552