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    <Class rdf:about="http://purl.obolibrary.org/obo/FLU_0000939">
        <rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">hemagglutinin typing</rdfs:label>
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                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/OBI_0000070"/>
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        <ns3:IAO_0000119 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">URL:http://www.springerprotocols.com/Full/doi/10.1007/978-1-59745-279-3_8?encCode=REZJOjhfMy05NzItNTQ3OTUtMS04Nzk=&amp;tokenString=ycLy0AkcLqNgMccOI6y30w==</ns3:IAO_0000119>
        <ns3:IAO_0000115 xml:lang="en">An assay which aims at determining the hemagglutanin subtype of an influenza virus.</ns3:IAO_0000115>
        <ns3:IAO_0000118 xml:lang="en">HA typing</ns3:IAO_0000118>
        <ns3:IAO_0000232 xml:lang="en">MC, 20101202: made it a defined class as there are several methods to identify the heagglutinin type as per http://www.sciencedirect.com/science?_ob=ArticleURL&amp;_udi=B6T32-4C47KNC-5&amp;_user=1022551&amp;_coverDate=07%2F31%2F2004&amp;_rdoc=1&amp;_fmt=high&amp;_orig=search&amp;_origin=search&amp;_sort=d&amp;_docanchor=&amp;view=c&amp;_searchStrId=1565330571&amp;_rerunOrigin=google&amp;_acct=C000050484&amp;_version=1&amp;_urlVersion=0&amp;_userid=1022551&amp;md5=c5d1a3bc08abe655acb70076b13e3a74&amp;searchtype=a

The haemagglutination-inhibition assay that is routinely used for subtyping and antigenic characterisation of influenza  strains does not distinguish between A(H1N1) and A(H1N2) strains; therefore, alternative tests are required for typing the NA. The standard test used to determine neuraminidase type is a rather cumbersome and time-consuming procedure (approximately 18 h) which relies on inhibition, by antibody, of n-acetyl neuraminic acid release from a substrate such as fetuin  (Aymard-Henry et al., 1973). Alternative methods of neuraminidase assay have been described, one for example relying on the agglutination of neuraminidase-treated erythrocytes by lectins (Fiszon and Hannoun, 1990 B Fiszon and C Hannoun, Comparison of neuraminidases of the same subtype but from different species using a new method of titration, J. Virol. Methods 27 (1990), pp. 79–90. Abstract  |  PDF (587 K)  | View Record in Scopus | Cited By in Scopus (4)Fiszon and Hannoun, 1990)</ns3:IAO_0000232>
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        <rdfs:label>hemagglutinin</rdfs:label>
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