continent South America A continent of the Americas, situated entirely in the Western Hemisphere and mostly in the Southern Hemisphere, with about a quarter in the Northern Hemisphere. It is bordered on the west by the Pacific Ocean and on the north and east by the Atlantic Ocean. North America and the Caribbean Sea lie to the northwest. LanguaL curation note: US FDA 1995 Code: QV continent South America A continent of the Americas, situated entirely in the Western Hemisphere and mostly in the Southern Hemisphere, with about a quarter in the Northern Hemisphere. It is bordered on the west by the Pacific Ocean and on the north and east by the Atlantic Ocean. North America and the Caribbean Sea lie to the northwest. LanguaL curation note: US FDA 1995 Code: QV