midwestern states State of Arkansas A state located in the southern region of the United States. Arkansas shares a border with six states, with its eastern border largely defined by the Mississippi River. Arkansas shares its southern border with Louisiana, its northern border with Missouri, its eastern border with Tennessee and Mississippi, and its western border with Texas and Oklahoma. LanguaL curation note: US FDA 1995 Code: US05 arkansas State of Arkansas A state located in the southern region of the United States. Arkansas shares a border with six states, with its eastern border largely defined by the Mississippi River. Arkansas shares its southern border with Louisiana, its northern border with Missouri, its eastern border with Tennessee and Mississippi, and its western border with Texas and Oklahoma. LanguaL curation note: US FDA 1995 Code: US05 arkansas