Commonwealth of Puerto Rico A semi-autonomous territory composed of an archipelago in the northeastern Caribbean, east of the Dominican Republic and west of the Virgin Islands, approximately 2,000 km off the coast of Florida (the nearest of the mainland United States). LanguaL curation note: US FDA 1995 Code: PR puerto rico Caribbean Region Commonwealth of Puerto Rico A semi-autonomous territory composed of an archipelago in the northeastern Caribbean, east of the Dominican Republic and west of the Virgin Islands, approximately 2,000 km off the coast of Florida (the nearest of the mainland United States). LanguaL curation note: US FDA 1995 Code: PR puerto rico Caribbean Region