part of part of develops from develops from developmentally induced by developmentally induced by tissue neurectoderm eye primordium ectoderm-derived structure optic vesicle http://upload.wikimedia.org/wikipedia/commons/e/e0/Gray863.png ocular vesicle EHDAA2:0001320 NCIT:C34236 eye vesicle optic vesicles UBERON:0004128 SCTID:362864008 The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup[GO]. Portion of tissue that is comprised of neuroepitheium which has pinched off from the anterior neural keel and will form the optic cup[ZFA]. ZFA:0000050 TAO:0000050 evagination AAO:0011039 UMLS:C0231106 FMA:293357 EMAPA:16540 VHOG:0000165 Wikipedia:Optic_vesicles (...) an essentially similar sequence of events occurs during the embryonic development of the vertebrate eye. The eye initially develops as a single median evagination of the diencephalon that soon bifurcates to form the paired optic vesicles.[well established][VHOG] XAO:0000228 Genes: Six3, Pax6, Rx1 are expressed together in the tip of the neural plate [ISBN:9780878932504 "Developmental Biology"]. Development notes: During subsequent develop- ment, the optic vesicle invaginates and becomes a two-layered structure with an inner neural retina and outer retinal pigment epithelium. As soon as the developing optic vesicle makes contact with the overlying ectoderm, it induces the ectoderm to thicken and form the lens placode [PMID:16496288] chordamesoderm immature eye