connects connects metacarpal bone of digit 1 carpometacarpal joint carpometacarpal joint of digit 1 TMJ trapeziometacarpal joint carpometacarpal joint of thumb In humans it connects the trapezium to the first metacarpal bone, plays an irreplaceable role in the normal functioning of the thumb. The most important joint connecting the wrist to the metacarpus, osteoarthritis of the TMC is a severely disabling condition; up to twenty times more common among old women than in average carpometacarpal joint of the thumb carpometacarpal joint of pollex UBERON:0011265 carpometacarpal joint of digit I SCTID:361843007 Wikipedia:Carpometacarpal_joint#Thumb A carpometacarpal joint that connects to metacarpal 1. FMA:35421