abnormal chromatin silencing abnormal chromatin silencing at centromere midori FYPO:0000146 Chromatin silencing phenotypes may reflect the assembly or maintenance of heterochromatin or CENP-A-containing chromatin. See the GO cellular component terms 'heterochromatin' (GO:0000792) and 'CENP-A containing chromatin' (GO:0061638), and the biological process terms 'heterochromatin organization' (GO:0070828) and 'CENP-A containing chromatin organization' (GO:0061641). abnormal chromatin silencing at centromere during mitotic cell cycle 2011-04-13T03:34:54Z A transcription regulation phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing is abnormal in centromeric regions. Chromatin silencing is the observed effect of processes that repress transcription in a region of the genome that is normally assembled into heterochromatin or CENP-A-containing chromatin (the latter is found at the centromere central core). abnormal heterochromatin silencing at centromere abnormal chromatin silencing at centromere during vegetative growth