obsolete genome stability defects true genome stability defects during mitotic cell cycle midori genome stability defects during vegetative growth 2011-04-19T02:59:38Z FYPO:0000241 OBSOLETE. A cell phenotype observed in the vegetative growth phase of the life cycle in which any process that affects the physical integrity, replication, or segregation of genomic DNA is abnormal. Encompasses effects on DNA metabolism, chromosome organization, the spindle assembly checkpoint, and any DNA integrity checkpoint. This term was made obsolete because it groups a number of somewhat related phenomena, but was not defined clearly or precisely.