abnormal CENP-A containing chromatin assembly decreased spatial extent of CENP-A containing chromatin assembly reduced spatial extent of CENP-A containing nucleosome assembly 2015-01-21T14:17:27Z decreased extent of CENP-A containing nucleosome A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromatin containing the histone H3 variant CenH3 (also called CENP-A; Cnp1 in S. pombe) are assembled over a smaller portion of the centromeric region of the chromosome than normal. CENP-A-containing nucleosomes are normally assembled into chromatin at the centromeres, encompassing the central core and centromeric inner repeat regions. decreased spatial extent of centromere-specific nucleosome assembly decreased spatial extent of centromeric DNA replication-independent nucleosome assembly FYPO:0004322 decreased spatial extent of centromere-specific histone exchange decreased spatial extent of CENP-A deposition decreased spatial extent of CENP-A containing nucleosome assembly during vegetative growth decreased spatial extent of CENP-A containing nucleosome assembly decreased spatial extent of CENP-A loading decreased spatial extent of CENP-A containing nucleosome assembly during mitotic cell cycle decreased spatial extent of DNA replication-independent nucleosome assembly at centromere decreased spatial extent of CenH3-containing nucleosome assembly at centromere decreased spatial extent of CENP-A containing nucleosome assembly at centromere midori