has_part during inheres_in qualifier has_output cut abnormal response to mitotic cell cycle spindle assembly checkpoint signaling mitotic spindle assembly checkpoint override mitotic SAC override A cellular process phenotype in which a mitotic cell cycle arrest that normally occurs in response to mitotic cell cycle spindle assembly checkpoint signaling does not occur. As a result, the septation initiation network (SIN) signaling pathway is activated despite activation of the mitotic spindle assembly checkpoint (SAC). Normally, under conditions that activate the SAC, SIN activation is inhibited and the cell cycle arrests in anaphase. In this phenotype, premature SIN activation leads to premature cytokinesis and the formation of cut cells. midori 2015-04-02T14:10:40Z abolished response to mitotic cell cycle spindle assembly checkpoint signaling SIN activation in presence of active mitotic SAC mitotic cell cycle spindle assembly checkpoint override septation initiation signaling activation in presence of active mitotic spindle assembly checkpoint FYPO:0004537