abnormal protein-protein interaction altered protein binding specificity midori abnormal protein binding specificity altered protein-protein interaction specificity Also consider annotating to another term under 'abnormal protein binding', such as 'increased protein binding' (FYPO:0001571), to capture more details about the effect on protein binding specificity. FYPO:0005119 2015-12-14T12:00:51Z A molecular function phenotype in which a mutation causes a gene product to bind to one or more proteins with different specificity from normal. For example, a protein may bind to a protein in a mutant that it does not bind in wild type. The affected gene product may be encoded by the mutated gene, or by a different gene.