normal cellular process during vegetative growth normal spatio-temporal regulation of replication fork localization normal replication foci dynamics normal spatio-temporal replication fork organization normal replication focus organization normal spatio-temporal regulation of replication fork localization during mitotic cell cycle midori FYPO:0005166 normal spatio-temporal regulation of replication fork localization during vegetative growth 2015-12-18T14:17:18Z normal spatio-temporal regulation of replication fork localisation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the spatio-temporal pattern of localization of replication forks into nuclear foci is normal (i.e. indistinguishable from wild type). Normally, replication forks appear organized into foci outside the nucleolus in early S phase. As S phase progresses, the number of foci first increases, then decreases, and the remaining foci concentrate within the nucleolus or at the nucleolar periphery. The last replication foci remaining at the end of S phase are one or two large spots at the nucleolar border.