abnormal replication fork processing increased mitotic sister chromatid bridge formation during replication fork processing anaphase bridge formation following replication fork processing A cell phenotype in which one or more bridges consisting of unresolved intertwined sister chromatids form following replication fork arrest, and persist until mitotic anaphase. Bridges contain dsDNA and RPA-bound ssDNA, and may break, resulting in unequal sister chromatid segregation. midori FYPO:0006086 2017-06-28T14:25:09Z