decreased gross chromosomal rearrangement decreased isochromosome formation 2020-06-30T15:25:04Z reduced isochromosome formation decreased isochromosome formation during vegetative growth decreased isochromosome formation during mitotic cell cycle midori FYPO:0007423 A cell phenotype in which isochromosome formation occurs less frequently than in wild type cells. In isochromosome formation, one chromosome arm is lost and the other arm is duplicated in its place. decreased occurrence of isochromosome formation