abnormal nucleosome positioning in heterochromatin decreased nucleosome occupancy decreased nucleosome occupancy at centromeric heterochromatin 2024-01-19T11:21:29Z vw decreased nucleosome occupancy at centromeric region A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome occupancy is lower than normal in the pericentromeres. Nucleosome occupancy measures the tendency for DNA in a given region to be packaged into nucleosomes.