abnormal protein localization to chromatin during vegetative growth decreased protein localization to subtelomeric chromatin knob during vegetative growth 2026-04-01T08:32:51Z A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin knobs in subtelomeric regions is decreased. Chromatin knobs are highly condensed chromatin bodies that are distinct from subtelomeric heterochromatin (observed on chromosomes 1 and 2). PomBase:pc We recommend noting which protein(s) were used in the assay when annotating to this term.