obsolete sterol regulatory element binding protein cleavage true GO:0006992 OBSOLETE. The proteolytic release of a transcriptionally active sterol regulatory element binding protein (SREBP) from intracellular membranes, freeing it to move to the nucleus to upregulate transcription of target genes, in response to altered levels of one or more lipids. SREBP cleavage This term was obsoleted because it represents a molecular function. sterol depletion response, SREBP cleavage GO:0035103 sterol regulatory element binding protein cleavage involved in ER-nuclear sterol response pathway biological_process