histone H4 PR:000008603 A core histone that is a translation product of the human HIST4H4 genes, 1:1 orthologs thereof, or a semi-ortholog thereof. Category=gene. Note: The human The HIST1H4A, HIST1H4B, HIST1H4C, HIST1H4D, HIST1H4E, HIST1H4F, HIST1H4H, HIST1H4I, HIST1H4J, HIST1H4K, HIST1H4L, HIST2H4A, HIST2H4B, and HIST4H4 genes encode identical proteins. protein core histone