pyrimidinemonocarboxylic acid
organofluorine compound
nucleobase analogue
5-fluoroorotic acid
5-fluoro-6-carboxyuracil
PMID:2675756
A pyrimidinemonocarboxylic that is orotic acid which is substituted by fluorine at position 5. It is used in yeast molecular genetics to detect expression of the URA3 gene, which encodes orotine-5'-monophosphate dicarboxylase. A yeast with and active URA3 gene converts 5-fluoroorotic acid to fluorodeoxyuridine, which is toxic to cells.
CHEBI:74498
Ro 2-9945
FOA
PMID:3586772
ENT-26398
CAS:703-95-7
FO
Patent:US2948725
1,2,3,6-tetrahydro-2,6-dioxo-5-fluoro-4-pyrimidinecarboxylic acid
PMID:3323810
5-fluoro-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid
NSC 31712
NSC-31712
Patent:GB806584
Reaxys:181933
5-fluorouracil-4-carboxylic acid
chebi_ontology
5-fluoro-1,2,3,6-tetrahydro-2,6-dioxo-4-pyrimidinecarboxylic acid