amino cyclitol glycoside aminoglycoside antibiotic paromomycin An amino cyclitol glycoside that is the 1-<em>O</em>-(2-amino-2-deoxy-α-<small>D</small>-glucopyranoside) and the 3-<em>O</em>-(2,6-diamino-2,6-dideoxy-β-<small>L</small>-idopyranosyl)-β-<small>D</small>-ribofuranoside of 4,6-diamino-2,3-dihydroxycyclohexane (the 1<i>R</i>,2<i>R</i>,3<i>S</i>,4<i>R</i>,6<i>S</i> diastereoisomer). It is obtained from various <em>Streptomyces</em> species. A broad-spectrum antibiotic, it is used (generally as the sulfate salt) for the treatment of acute and chronic intestinal protozoal infections, but is not effective for extraintestinal protozoal infections. It is also used as a therapeutic against visceral leishmaniasis. CHEBI:44703