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    <!-- http://purl.obolibrary.org/obo/HP_0000737 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/HP_0000737">
        <rdfs:label>Irritability</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/HP_0031467"/>
        <oboInOwl:hasExactSynonym>Easily annoyed</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Quick-temper</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Irritable mood</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Irritable</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Grumpy</oboInOwl:hasExactSynonym>
        <oboInOwl:hasBroadSynonym>Dysphoric agitation</oboInOwl:hasBroadSynonym>
        <rdfs:comment>Consider the context of the individual experience; the state of being irritable implies a change from a recognized baseline. Irritability as a trait implies an enduring feature (years) of the individual.</rdfs:comment>
        <oboInOwl:hasExactSynonym>Irritability</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Short fuse</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Easily upset</oboInOwl:hasExactSynonym>
        <oboInOwl:hasBroadSynonym>Frustration intolerance</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasBroadSynonym>Increased emotional sensitivity</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasDbXref>UMLS:C2700617</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Easily bothered</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>On edge</oboInOwl:hasExactSynonym>
        <ns2:IAO_0000115>An emotional state characterized by negative feelings of heightened frustration, annoyance, or feeling upset, often triggered by internal factors (e.g., fatigue, hunger, unfulfilled desires) or external factors (e.g., social or environmental challenges). Irritability may be unpredictable, and is accompanied by a lowered threshold for emotional reactivity and observable features (speech, facial expressions, or psychomotor activity).</ns2:IAO_0000115>
        <oboInOwl:hasBroadSynonym>Increased emotional instability</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasExactSynonym>Short tempered</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Cranky</oboInOwl:hasExactSynonym>
        <oboInOwl:hasBroadSynonym>Emotional overactivity</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasBroadSynonym>Heightened reactivity state</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasBroadSynonym>Exasperation</oboInOwl:hasBroadSynonym>
        <oboInOwl:hasExactSynonym>Hot-temper</oboInOwl:hasExactSynonym>
        <oboInOwl:hasBroadSynonym>Behavioral irritation state</oboInOwl:hasBroadSynonym>
        <ns2:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/hp.owl"/>
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    <!-- http://purl.obolibrary.org/obo/HP_0031467 -->

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        <rdfs:label>Dysregulated negative emotional state</rdfs:label>
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