vascular disorder vasculitis icd11.foundation:572581721 Orphanet:52759 MEDGEN:12054 Wikipedia:Vasculitis MedDRA:10036023 Vasculitis represents a clinically heterogenous group of diseases of multifactorial etiology characterized by inflammation of either large-sized vessels (large-vessel vasculitis, e.g. Giant-cell arteritis and Takayasu arteritis), medium-sized vessels (medium-vessel vasculitis e.g. polyarteritis nodosa and Kawasaki disease), or small-sized vessels (small-vessel vasculitis, e.g. granulomatosis with polyangiitis, microscopic polyangiitis, immunoglobulin A vasculitis, and cutaneous leukocytoclastic angiitis). Vasculitis occurs at any age, may be acute or chronic, and manifests with general symptoms such as fever, weight loss and fatigue, as well as more specific clinical signs depending on the type of vessels and organs affected. The degree of severity is variable, ranging from life or sight threatening disease (e.g. Behcet disease) to relatively minor skin disease. NCIT:C26912 EFO:0006803 UMLS:C0042384 DOID:865 MESH:D014657 GARD:0018844 SCTID:31996006 systemic vasculitis MedDRA:10047115 inflammatory disease