immune system disorder cytokine release syndrome cytokine-associated toxicity MEDGEN:215297 UMLS:C0948245 NCIT:C78251 A syndrome that occurs after therapeutic infusion of antibodies into the blood and is characterized by nausea, headache, tachycardia, hypotension, rash, and shortness of breath. It is caused by the release of cytokines from the cells that are targeted by the antibodies. Most patients experience a mild to moderate reaction; however, the reaction may be severe and life-threatening. CRS cytokine storm MESH:D000080424