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    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000231"/>
    


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    <!-- http://purl.obolibrary.org/obo/GENO_0000955 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/GENO_0000955">
        <rdfs:label>obsolete variant copy number complement</rdfs:label>
        <deprecated rdf:datatype="http://www.w3.org/2001/XMLSchema#boolean">true</deprecated>
        <ns3:IAO_0000231>Decided to implement copy number related classes at the sequence level, rather than the sequence feature level.</ns3:IAO_0000231>
        <rdfs:comment>In a &#39;normal&#39; diploid genome, the copy number complement for any feature (on a non-Y chromosome) contains two members.  A copy number variation occurs when a complement contains more or less than two members - as the result of deletion or duplication event(s).

Note that the &#39;copy number variation&#39; class in GENO is related to but ontologically distinct form the SO &#39;copy_number_variation&#39; class. The GENO class refers to a *set* of all copies of a sequence in a genome, where the number of members in the set is in conflict with the genome&#39;s normal ploidy (e.g. not two for a diploid genome). The SO class, which is defined as a sequence feature level concept and therefore represents a single continuous extent of sequence, refers to a single copy of duplicated (or deleted) sequence that comprises the set defined by the GENO CNV class.</rdfs:comment>
        <ns3:IAO_0000115>A copy number complement&#39; that has an abnormal number of members (e.g. more or less than two for an autosomal sequence in a diploid genome, as a result of deletion or duplication event(s).</ns3:IAO_0000115>
        <ns3:IAO_0000118 xml:lang="en">copy number variation</ns3:IAO_0000118>
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