L-histidine biosynthetic process https://github.com/geneontology/go-ontology/issues/31525 histidine biosynthesis biological_process histidine anabolism MetaCyc:HISTSYN-PWY The chemical reactions and pathways resulting in the formation of L-histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid. histidine biosynthetic process histidine synthesis GO:0000105 MetaCyc:PWY-5029 histidine formation aromatic amino acid biosynthetic process imidazole-containing compound metabolic process L-amino acid biosynthetic process proteinogenic amino acid biosynthetic process