ribonuclease MRP activity https://github.com/geneontology/go-ontology/issues/22261 https://github.com/geneontology/go-ontology/issues/24408 molecular_function GO:0000171 Catalysis of the site-specific cleavage of RNA by a catalytic RNA-mediated mechanism; substrates include the A3 site in the ITS1 of pre-rRNA. Wikipedia:RNase_MRP RNase MRP RNA endonuclease activity hydrolase activity, acting on ester bonds