RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II core promoter proximal region sequence-specific DNA binding krc Binding to a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in cis relative to the transcription start site (i.e., on the same strand of DNA) of a gene transcribed by RNA polymerase II. molecular_function RNA polymerase II proximal promoter sequence-specific DNA binding 2010-08-10T02:17:19Z RNA polymerase II distal enhancer sequence-specific DNA binding GO:0000980 RNA polymerase II promoter proximal region sequence-specific DNA binding RNA polymerase II upstream activating sequence (UAS) sequence-specific DNA binding Note that the phrase "upstream activating sequence", or UAS is often used in S. cerevisiae literature to refer to cis-regulatory sequences. In bacteria such as E. coli, the phrase "upstream activating sequence", or UAS is usually a synonym for "enhancer". Reactome:R-HSA-400204 GO:0000978 cis-regulatory region sequence-specific DNA binding