part of DNA-templated transcription open complex formation transcription open complex formation at RNA polymerase II promoter RNA polymerase II promoter melting biological_process transcriptional open complex formation at RNA polymerase II promoter krc Any process involved in the melting of the DNA hybrid of the core promoter region within the transcriptional closed complex of an RNA polymerase II preinitiation complex (PIC) to produce an open complex where the DNA duplex around the transcription initiation site is unwound to form the transcription bubble. GO:0001113 2010-12-02T02:27:19Z transcription initiation at RNA polymerase II promoter