obsolete extrachromosomal circular DNA accumulation involved in replicative cell aging https://github.com/geneontology/go-ontology/issues/20007 true This term was obsoleted because it represents an assay, not a true biological process. extrachromosomal circular DNA accumulation during replicative cell ageing extrachromosomal circular DNA accumulation during replicative cell aging OBSOLETE. Increase in abundance of circular DNA molecules in dividing cells as they age. These molecules originate in the chromosome but are excised and circularized, often by intramolecular homologous recombination between direct tandem repeats, and then replicated independently of chromosomal replication. biological_process GO:0001307